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  • The Adventures of Superoxide Dismutase in Health and ...

    Xu, Y., Porntadavity, S., and St Clair, D. K. (2002). Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2). Biochem J 362, 401–412. PubMed CrossRef Google Scholar

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  • Superoxide Dismutase (SOD) And Its Role In Maintaining ...

    Superoxide dismutase (SOD) is an antioxidant enzyme produced in our bodies to neutralize a specific oxygen-derived free radical called superoxide. Oxygen that we breathe in is a source of life, but at the same time it can cause damage in the body by creating oxygen free radicals, molecules that become unstable by losing or gaining an electron ...

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  • (PDF) Up-Regulation of Superoxide Dismutase 2 in 3D ...

    2020-1-11u2002·u2002Up-Regulation of Superoxide Dismutase 2 in 3D Spheroid Formation Promotes Therapeutic Potency of Human Umbilical Cord Blood-Derived Mesenchymal …

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  • Molecules

    Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant defense against oxidative stress in the body. SOD supplementation may therefore trigger the endogenous antioxidant machinery for the neutralization of free-radical excess and be used in a variety of pathological settings. This paper aimed to provide an extensive review of the possible uses of SODs in a range ...

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  • Extracellular Superoxide Dismutase Is Associated With Left ...

    2020-7-29u2002·u2002Superoxide dismutase multigene family: a comparison of the CuZn‐SOD (SOD1), Mn‐SOD (SOD2), and EC‐SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med. 2002; 33:337–349. Crossref Medline Google Scholar; 12 Oury TD, Day BJ, Crapo JD. Extracellular superoxide dismutase in vessels and airways of humans and baboons.

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  • Comparison of the determination of superoxide dismutase ...

    2000-11-1u2002·u2002The superoxide dismutase activity is then measured by the degree of inhibition of this reaction by means of the decrease in absorbance at 505 nm, 37°C. Washed RBC from 0.5 ml of whole blood was made up to 2.0 ml with cold redistilled water, mixed and left to stand at 4°C for 15 min.

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  • Perfluorochemical Liquids Enhance Delivery of Superoxide ...

    2006-7-1u2002·u2002McElroy MC, Postle AD, Kelly FJ 1992 Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development. Biochim Biophys Acta 1117 : 153–158

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  • Superoxide dismutase assay using alkaline ...

    1983-12-1u2002·u2002Alkaline dimethylsulfoxide as a superoxide anion-generating system in association with cytochrome c as a superoxide anion-indicating scavenger has been used to develop a new assay for superoxide dismutase. The assay is sensitive (one unit of enzymatic activity is provided by 110 ng of purified copper-containing superoxide dismutase) and highly specific.

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  • GliSODin®

    GliSODin, the only orally-effective SOD supplement, is protected by international patents and U.S. patents 6,045,809 and 6,426,068B1, with additional patents pending. GliSODin's effectiveness is due to the two unique compounds from which its name is derived, Gliadin and SOD. First, GliSODin provides a melon source of SOD.

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  • Cu,Zn–Superoxide Dismutase–Mediated Redox Regulation

    2015-6-2u2002·u2002Human monocyte (THP-1) and murine alveolar macrophage (MH-S) cell lines were obtained from American Type Culture Collection (Manassas, VA). Cells were maintained in RPMI-1640 media with following supplements: 10% fetal bovine serum and penicillin/streptomycin. All experiments were performed with 0.5% serum supplement.

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  • How To Boost The Superoxide Dismutase - Life Extension

    2021-9-18u2002·u2002The enzyme superoxide dismutase (SOD) is one of the body's foremost antioxidant defenses, reducing free radical damage associated with atherosclerosis, stroke, and arthritis. New bioavailable forms of SOD offer superior protection against oxygen free radicals. Scientifically reviewed by: Dr. Gary Gonzalez, MD, on January 2021.

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  • Placental superoxide dismutase 3 mediates benefits of ...

    2021-5-4u2002·u2002Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health Author links open overlay panel Joji Kusuyama 1 2 Ana Barbara Alves-Wagner 1 Royce H. Conlin 1 Nathan S. Makarewicz 1 Brent G. Albertson 1 Noah B. Prince 1 Shio Kobayashi 3 Chisayo Kozuka 1 4 Magnus Møller 5 Mette Bjerre 6 Jens Fuglsang 5 Emily Miele 1 ...

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  • Extracellular Superoxide Dismutase Is Associated With Left ...

    2020-7-29u2002·u2002Superoxide dismutase multigene family: a comparison of the CuZn‐SOD (SOD1), Mn‐SOD (SOD2), and EC‐SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med. 2002; 33:337–349. Crossref Medline Google Scholar; 12 Oury TD, Day BJ, Crapo JD. Extracellular superoxide dismutase in vessels and airways of humans and baboons.

    Get Price
  • CAS No.9054-89-1,Dismutase, superoxide Suppliers,MSDS

    9054-89-1. High quality Dismutase, superoxide supplier in China Manufacturer 9054-89-1. Min.Order: 1 Kilogram. FOB Price: USD $ 100.0-150.0/Kilogram. Our company: Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kinds ...

    Get Price
  • Comparison of the determination of superoxide dismutase ...

    2000-11-1u2002·u2002The superoxide dismutase activity is then measured by the degree of inhibition of this reaction by means of the decrease in absorbance at 505 nm, 37°C. Washed RBC from 0.5 ml of whole blood was made up to 2.0 ml with cold redistilled water, mixed and left to stand at 4°C for 15 min.

    Get Price
  • Perfluorochemical Liquids Enhance Delivery of Superoxide ...

    2006-7-1u2002·u2002McElroy MC, Postle AD, Kelly FJ 1992 Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development. Biochim Biophys Acta 1117 : 153–158

    Get Price
  • The activity of superoxide dismutases (SODs) at the early ...

    2018-3-20u2002·u2002Unbound tetrapyrroles, i.e. protochlorophyllide (Pchlide), chlorophyllide and chlorophylls, bring the risk of reactive oxygen species (ROS) being generated in the initial stages of angiosperm deetiolation due to inefficient usage of the excitation energy for photosynthetic photochemistry. We analyzed the activity of superoxide dismutases (SODs) in etiolated wheat (Triticum aestivum) leaves …

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  • Extracellular Superoxide Dismutase: Growth Promoter or ...

    2016-5-12u2002·u2002Extracellular superoxide dismutase (SOD3) gene transfer to tissue damage results in increased healing, increased cell proliferation, decreased apoptosis, and decreased inflammatory cell infiltration. At molecular level, in vivo SOD3 overexpression reduces superoxide anion () concentration and increases mitogen kinase activation suggesting that ...

    Get Price
  • Superoxide Dismutase Administration, A Potential Therapy ...

    2013-6-21u2002·u2002Oxidative stress, involved in many diseases, is defined as an impaired balance between reactive oxygen species (ROS) production and antioxidant defences. Antioxidant enzymes such as superoxide dismutase (SOD) play a key role in diminishing oxidative stress. Thus, the removal of ROS by exogenous SODs could be an effective preventive strategy against various diseases. The poor …

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  • Superoxide Dismutase (SOD) Colorimetric Activity Kit

    The Superoxide Dismutase Activity kit is designed to quantitatively measure SOD activity in a variety of samples. The assay measures all types of SOD activity, including Cu/Zn, Mn, and FeSOD types. A bovine erythrocyte SOD standard is provided to generate a standard curve for the assay and all samples should be read off of the standard curve.

    Get Price
  • CAS No.9054-89-1,Dismutase, superoxide Suppliers,MSDS

    9054-89-1. High quality Dismutase, superoxide supplier in China Manufacturer 9054-89-1. Min.Order: 1 Kilogram. FOB Price: USD $ 100.0-150.0/Kilogram. Our company: Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kinds ...

    Get Price
  • GliSODin®

    GliSODin, the only orally-effective SOD supplement, is protected by international patents and U.S. patents 6,045,809 and 6,426,068B1, with additional patents pending. GliSODin's effectiveness is due to the two unique compounds from which its name is derived, Gliadin and SOD. First, GliSODin provides a melon source of SOD.

    Get Price
  • Role of Vascular Extracellular Superoxide Dismutase in ...

    2011-7-5u2002·u2002Introduction. Reactive oxygen species, and in particular the superoxide anion (O 2 ·−), play a critical role in the genesis of hypertension via mechanisms that are incompletely understood.Experimental hypertension is ameliorated by treatment with membrane-targeted forms of superoxide dismutase (SOD) or by SOD mimetics, 1,2 and mice lacking the NADPH oxidase subunit p47 phox have reduced ...

    Get Price
  • Placental superoxide dismutase 3 mediates benefits of ...

    Kusuyama et al. define a novel mechanism for placental transmission of improved metabolic health to offspring. SOD3 is identified as an exercise-induced and vitamin D-regulated placenta-derived protein that improves glucose homeostasis in offspring. SOD3 activates an AMPK/TET signaling axis resulting in epigenetic changes to metabolic genes in offspring liver.

    Get Price
  • Oxidative stress and antioxidant status in dairy cows ...

    2015-7-9u2002·u2002Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods Jana Konvičná 1, Mária Vargová, Iveta Paulíková, Gabriel Kováč, Zuzana Kostecká2 University of Veterinary Medicine and Pharmacy, 1Clinic of Ruminants, 2Department of Chemistry, Biochemistry and Biophysics, Košice, Slovak Republic

    Get Price
  • Perfluorochemical Liquids Enhance Delivery of Superoxide ...

    2006-7-1u2002·u2002McElroy MC, Postle AD, Kelly FJ 1992 Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development. Biochim Biophys Acta 1117 : 153–158

    Get Price
  • Extracellular Superoxide Dismutase Regulates Early ...

    2020-1-14u2002·u2002Chronic hypoxia leads to pathologic remodeling of the pulmonary vasculature and pulmonary hypertension (PH). The antioxidant enzyme extracellular superoxide dismutase (SOD3) protects against ...

    Get Price
  • Tempol

    Tempol is a small-molecule cell-permeable superoxide dismutase (SOD) mimetic that is able to act as SOD1, SOD2, SOD3 and catalase in vivo.[NOT to be confused with the 'Tempol' brand of paracematol, also known as acetaminophen, an over-the-counter analgesic that is a generic form of Tylenol®]

    Get Price
  • Extracellular Superoxide Dismutase: Growth Promoter or ...

    2016-5-12u2002·u2002Extracellular superoxide dismutase (SOD3) gene transfer to tissue damage results in increased healing, increased cell proliferation, decreased apoptosis, and decreased inflammatory cell infiltration. At molecular level, in vivo SOD3 overexpression reduces superoxide anion () concentration and increases mitogen kinase activation suggesting that ...

    Get Price
  • Superoxide Dismutase (SOD) Colorimetric Activity Kit

    The Superoxide Dismutase Activity kit is designed to quantitatively measure SOD activity in a variety of samples. The assay measures all types of SOD activity, including Cu/Zn, Mn, and FeSOD types. A bovine erythrocyte SOD standard is provided to generate a standard curve for the assay and all samples should be read off of the standard curve.

    Get Price
  • CAS No.9054-89-1,Dismutase, superoxide Suppliers,MSDS

    9054-89-1. High quality Dismutase, superoxide supplier in China Manufacturer 9054-89-1. Min.Order: 1 Kilogram. FOB Price: USD $ 100.0-150.0/Kilogram. Our company: Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kinds ...

    Get Price
  • GliSODin®

    GliSODin, the only orally-effective SOD supplement, is protected by international patents and U.S. patents 6,045,809 and 6,426,068B1, with additional patents pending. GliSODin's effectiveness is due to the two unique compounds from which its name is derived, Gliadin and SOD. First, GliSODin provides a melon source of SOD.

    Get Price
  • Role of Vascular Extracellular Superoxide Dismutase in ...

    2011-7-5u2002·u2002Introduction. Reactive oxygen species, and in particular the superoxide anion (O 2 ·−), play a critical role in the genesis of hypertension via mechanisms that are incompletely understood.Experimental hypertension is ameliorated by treatment with membrane-targeted forms of superoxide dismutase (SOD) or by SOD mimetics, 1,2 and mice lacking the NADPH oxidase subunit p47 phox have reduced ...

    Get Price
  • Placental superoxide dismutase 3 mediates benefits of ...

    Kusuyama et al. define a novel mechanism for placental transmission of improved metabolic health to offspring. SOD3 is identified as an exercise-induced and vitamin D-regulated placenta-derived protein that improves glucose homeostasis in offspring. SOD3 activates an AMPK/TET signaling axis resulting in epigenetic changes to metabolic genes in offspring liver.

    Get Price
  • Oxidative stress and antioxidant status in dairy cows ...

    2015-7-9u2002·u2002Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods Jana Konvičná 1, Mária Vargová, Iveta Paulíková, Gabriel Kováč, Zuzana Kostecká2 University of Veterinary Medicine and Pharmacy, 1Clinic of Ruminants, 2Department of Chemistry, Biochemistry and Biophysics, Košice, Slovak Republic

    Get Price
  • Perfluorochemical Liquids Enhance Delivery of Superoxide ...

    2006-7-1u2002·u2002McElroy MC, Postle AD, Kelly FJ 1992 Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development. Biochim Biophys Acta 1117 : 153–158

    Get Price
  • Extracellular Superoxide Dismutase Regulates Early ...

    2020-1-14u2002·u2002Chronic hypoxia leads to pathologic remodeling of the pulmonary vasculature and pulmonary hypertension (PH). The antioxidant enzyme extracellular superoxide dismutase (SOD3) protects against ...

    Get Price
  • Tempol

    Tempol is a small-molecule cell-permeable superoxide dismutase (SOD) mimetic that is able to act as SOD1, SOD2, SOD3 and catalase in vivo.[NOT to be confused with the 'Tempol' brand of paracematol, also known as acetaminophen, an over-the-counter analgesic that is a generic form of Tylenol®]

    Get Price
  • Extracellular Superoxide Dismutase: Growth Promoter or ...

    2016-5-12u2002·u2002Extracellular superoxide dismutase (SOD3) gene transfer to tissue damage results in increased healing, increased cell proliferation, decreased apoptosis, and decreased inflammatory cell infiltration. At molecular level, in vivo SOD3 overexpression reduces superoxide anion () concentration and increases mitogen kinase activation suggesting that ...

    Get Price
  • Superoxide Dismutase (SOD) Colorimetric Activity Kit

    The Superoxide Dismutase Activity kit is designed to quantitatively measure SOD activity in a variety of samples. The assay measures all types of SOD activity, including Cu/Zn, Mn, and FeSOD types. A bovine erythrocyte SOD standard is provided to generate a standard curve for the assay and all samples should be read off of the standard curve.

    Get Price
  • CAS No.9054-89-1,Dismutase, superoxide Suppliers,MSDS

    9054-89-1. High quality Dismutase, superoxide supplier in China Manufacturer 9054-89-1. Min.Order: 1 Kilogram. FOB Price: USD $ 100.0-150.0/Kilogram. Our company: Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kinds ...

    Get Price
  • GliSODin®

    GliSODin, the only orally-effective SOD supplement, is protected by international patents and U.S. patents 6,045,809 and 6,426,068B1, with additional patents pending. GliSODin's effectiveness is due to the two unique compounds from which its name is derived, Gliadin and SOD. First, GliSODin provides a melon source of SOD.

    Get Price
  • Role of Vascular Extracellular Superoxide Dismutase in ...

    2011-7-5u2002·u2002Introduction. Reactive oxygen species, and in particular the superoxide anion (O 2 ·−), play a critical role in the genesis of hypertension via mechanisms that are incompletely understood.Experimental hypertension is ameliorated by treatment with membrane-targeted forms of superoxide dismutase (SOD) or by SOD mimetics, 1,2 and mice lacking the NADPH oxidase subunit p47 phox have reduced ...

    Get Price
  • Placental superoxide dismutase 3 mediates benefits of ...

    Kusuyama et al. define a novel mechanism for placental transmission of improved metabolic health to offspring. SOD3 is identified as an exercise-induced and vitamin D-regulated placenta-derived protein that improves glucose homeostasis in offspring. SOD3 activates an AMPK/TET signaling axis resulting in epigenetic changes to metabolic genes in offspring liver.

    Get Price
  • Oxidative stress and antioxidant status in dairy cows ...

    2015-7-9u2002·u2002Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods Jana Konvičná 1, Mária Vargová, Iveta Paulíková, Gabriel Kováč, Zuzana Kostecká2 University of Veterinary Medicine and Pharmacy, 1Clinic of Ruminants, 2Department of Chemistry, Biochemistry and Biophysics, Košice, Slovak Republic

    Get Price
  • Perfluorochemical Liquids Enhance Delivery of Superoxide ...

    2006-7-1u2002·u2002McElroy MC, Postle AD, Kelly FJ 1992 Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development. Biochim Biophys Acta 1117 : 153–158

    Get Price
  • Extracellular Superoxide Dismutase Regulates Early ...

    2020-1-14u2002·u2002Chronic hypoxia leads to pathologic remodeling of the pulmonary vasculature and pulmonary hypertension (PH). The antioxidant enzyme extracellular superoxide dismutase (SOD3) protects against ...

    Get Price
  • Tempol

    Tempol is a small-molecule cell-permeable superoxide dismutase (SOD) mimetic that is able to act as SOD1, SOD2, SOD3 and catalase in vivo.[NOT to be confused with the 'Tempol' brand of paracematol, also known as acetaminophen, an over-the-counter analgesic that is a generic form of Tylenol®]

    Get Price
  • Extracellular Superoxide Dismutase: Growth Promoter or ...

    2016-5-12u2002·u2002Extracellular superoxide dismutase (SOD3) gene transfer to tissue damage results in increased healing, increased cell proliferation, decreased apoptosis, and decreased inflammatory cell infiltration. At molecular level, in vivo SOD3 overexpression reduces superoxide anion () concentration and increases mitogen kinase activation suggesting that ...

    Get Price
  • Superoxide dismutase price,buy Superoxide dismutase ...

    Product description Superoxide Dismutase, bovine erythrocytes. Packaging 10mg. Price $298. Updated 2021-03-22. Buy. Manufacturer Sigma-Aldrich. Product number SAB1303104. Product description ANTI-SOD3 (N-TERM) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution.

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  • Fc-Receptor-Mediated Intracellular Delivery of Cu/Zn ...

    2000-12-1u2002·u2002Using specific antibodies against bovine Cu/Zn-superoxide dismutase (EC 1.15.1.1, SOD1) we demonstrated that anti-SOD antibodies (IgG1) are able to promote the intracellular translocation of the antioxidant enzyme. The transduction signalling mediated by IgG1 immune complexes are known to promote a concomitant production of superoxide and nitric oxide leading to the production of ...

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  • Regulation of Cu-Zn superoxide dismutase on SCN2A in

    In order to evaluate SCN2A as a candidate gene for epileptic susceptibility and the use of a Cu-Zn superoxide dismutase (SOD) supplement as a potential therapy for epilepsy, SCN2A expression in the cortex and the correlation between SCN2A and Cu-Zn SOD in SH-SY5Y cells were examined. SCN2A expression and the concentration of Cu-Zn SOD in the cerebral cortexes of patients with primary and ...

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  • Alteration of Extracellular Superoxide Dismutase in ...

    2020-11-17u2002·u2002Background: Superoxide dismutases (SODs) are an important family of antioxidant enzymes that modulate reactive oxygen species levels. It is largely unknown which SOD isoform(s) change in vivo in idiopathic pulmonary arterial hypertension (IPAH) patients.Methods: A total of 133 consecutive adult IPAH patients who underwent bone morphogenetic protein receptor type 2 (BMPR2) genetic …

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  • The Aktâ FoxO3aâ manganese superoxide dismutase

    The Akt–FoxO3a–manganese superoxide dismutase pathway is involved in the regulation of oxidative stress in diabetic nephropathy Qian Lu1, Yunpeng Zhai 2,QianCheng2, Yaowu Liu2,XingGao 2, Ting Zhang, Yaqin Wei, Fan Zhang and Xiaoxing Yin1,2

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  • Myocardial Protective Effect of Extracellular Superoxide ...

    2014-2-15u2002·u2002Extracellular superoxide dismutase (ecSOD) binds to heparin sulfate proteoglycans on cellular surface as a unique scavenger of superoxide anions in the extracellular space . Many studies have shown that direct gene transfer of the cDNA encoding membrane-bound human ecSOD affords transient cardio-protective effect [ 3, 5 ].

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  • The Akt–FoxO3a–manganese superoxide dismutase

    2012-11-22u2002·u2002Manganese superoxide dismutase is the downstream target protein of FoxO3a, which is the major ROS-detoxifying enzyme in cells. Manganese superoxide dismutase plays an important role in protecting the mitochondria from the deleterious effects of mitochondria-derived ROS (Holley et al. 2011).

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  • Frontiers

    2020-11-12u2002·u2002Superoxide dismutase (SOD) plays an essential role in eliminating oxidative damage of lactic acid bacteria. Streptococcus thermophilus, an important probiotic lactic acid bacterium, often inevitably suffers from various oxidative stress during dairy fermentation. In this study, to confer high-level oxidative resistance, the sod gene from Lactobacillus casei was heterologous expressed in S ...

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  • Enrichment of superoxide dismutase 2 in glioblastoma ...

    2019-10-19u2002·u2002Intratumor subsets with tumor-initiating features in glioblastoma are likely to survive treatment. Our goal is to identify the key factor in the process by which cells develop temozolomide (TMZ) resistance. Resistant cell lines derived from U87MG and A172 were established through long-term co-incubation of TMZ. Primary tumors obtained from patients were maintained as patient-derived …

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  • Roles of prostaglandin F2alpha and hydrogen peroxide in ...

    2012-10-26u2002·u2002Prostaglandin F2alpha (PGF) induces luteolysis in cow by inducing a rapid reduction in progesterone production (functional luteolysis) followed by tissue degeneration (structural luteolysis). However the mechanisms of action of PGF remain unclear. Reactive oxygen species (ROS) play important roles in regulating the luteolytic action of PGF. The local concentration of ROS is controlled …

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